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                  PerkinElmer

                  GPCR Research

                  G-protein coupled receptors (GPCR) are prominent targets in drug discovery. GPCRs are involved in most cellular responses to hormones and neurotransmitters and are essential for intracellular communication. Today, GPCR targeted drugs make up over a third of all approved drugs.

                  While GPCRs have been studied for decades, the complexities of these receptors in signaling are still being elucidated. As we better understand the role of GPCRs in different signaling pathways, such pathways are increasingly exploited for more targeted therapies, with fewer unwanted side effects.

                  PerkinElmer offers a variety of products to support GPCR research – for both functional and binding assays.?

                  • Scalable GPCR cellular imaging, detection instrumentation and liquid handling systems for radiometric fluorescence, luminescence or photometric detection
                  • Optimized cell-based GPCR assay platforms
                  • Versatile reagents—GPCR cell lines, frozen and ready-to-use cells, ligands and radioligands, and cloned receptor membranes
                  ?

                  For research use only. Not for use in diagnostic procedures.

                  GPCR Research Solutions

                  GPCR Research Reagents

                  GPCR research remains a widely studied area in drug discovery. As the complexity of the roles of GPCRs in signaling are unraveled, it is as important as ever to ...

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                  Microplate Readers

                  Performance, Versatility, and Reliability for Today’s Laboratory Needs As many of you know, microplate readers are instruments used to detect biological, chemic ...

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                  PerkinElmer Signals? Screening-Assay Data Management and Analysis Platform

                  Signals Screening is an assay data analysis and management platform that enables scientists to transform raw instrument data into actionable compound ID lists i ...

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                  Featured Products

                  EnVision Multimode Plate Reader

                  The EnVision? 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried an ...

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                  LANCE cAMP Detection Kit, 500 assay points

                  LANCE? TR-FRET cAMP assay kit, for Gs- and Gi-coupled GPCR functional assays.

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                  CGRP (human), [125I]-, 10μCi

                  Calcitonin gene-related peptide (CGRP), labeled with 125I. CGRP binds calcitonin receptors.

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                  cAMPZen Frozen cells, Adrenergic α2A, Human Recombinant, CHO-K1

                  Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.

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                  Explore other Therapeutic Target Areas

                  Biomarker Detection

                  Biomarker detection has become an integral part of both disease detection and treatment. The detection of biomarkers in pre-symptomatic patients leads to the ab ...

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                  Cell Signaling Analysis

                  From receptor ligand binding to intracellular pathway analysis of phosphorylated proteins, breakthrough discoveries in cell signaling a cell signal transduction ...

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                  Epigenetic Research

                  The study of gene expression is opening new doors for drug discovery. Our epigenetics solutions include cellular detection kits and epigenetic assays for reader ...

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                  Protein Kinase Research

                  Protein kinases are key focus targets in drug discovery. Kinases regulate most cellular pathways and are responsible for the modification of nearly a third of a ...

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                  Protein-Protein Interaction Research

                  Protein-protein interaction research is uncovering new targets for drug discovery in cancer and a variety of other diseases. However, measurement, modulation, a ...

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                  Contact us to see how we can help you unlock the door to the next targeted therapy

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