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                  PerkinElmer

                  Metabolic Disease

                  OF

                  Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

                  Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

                  Our products for metabolic disease research include:

                  • LANCE? TR-FRET technology
                  • AlphaLISA? immunoassay kits
                  • Alpha reagents for AlphaLISA
                  • DELFIA? TRF technology
                  • Cellular, tissue, and in vivo imaging systems
                  • Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

                  The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

                  Products & Services (134)
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                  Product Type
                  • Instruments (1)
                  • Reagents (130)
                  • Software and Informatics (3)
                  Assay Target
                  • Acetyl CoA carboxylase (1)
                  • Adiponectin (3)
                  • Albumin (5)
                  • AMPKα1/2 (1)
                  • ApoA1 (4)
                  • ApoB (2)
                  • ApoC3 (2)
                  • ApoE (2)
                  • AST (1)
                  • BMP-9 (1)
                  • C-peptide (2)
                  • CCL2 (1)
                  • Corticosterone (2)
                  • Cortisol (3)
                  • ERK1/2 (1)
                  • Factor VIII (1)
                  • FSH (3)
                  • Ghrelin (4)
                  • GLP-1 (2)
                  • Glucagon (2)
                  • Growth Hormone (1)
                  • hCG (3)
                  • HO-1 (1)
                  • HO-2 (1)
                  • IGF1 (5)
                  • IGF2 (1)
                  • Insulin (4)
                  • JNK1/2 (1)
                  • KIM-1 (1)
                  • LDH (1)
                  • Leptin (5)
                  • MANF (2)
                  • MBNL1 (1)
                  • NNMT (1)
                  • Osteoprotegerin (1)
                  • PCSK9 (1)
                  • PIGF (1)
                  • PON1 (1)
                  • PON2 (1)
                  • Rb (1)
                  • RB (2)
                  • Ribosmal Protein S6 (1)
                  • Ribosomal Protein S6 (2)
                  • S6 Ribosomal Protein (1)
                  • SHP2 (1)
                  • SMAD2 (1)
                  • Testosterone (1)
                  • TSH (4)
                  Application
                  • Protein Analysis & Detection (80)
                  • Protein Detection (8)
                  Therapeutic Area
                  • Angiogenesis (1)
                  • Biologics/Bioprocess (4)
                  • Cancer (2)
                  • Inflammation (8)
                  • Metabolic (58)
                  • Metabolic Disorders (1)
                  • Metabolism (8)
                  • Oncology (8)
                  Product Brand Name
                  • Alpha SureFire Multiplex (3)
                  • Alpha SureFire Ultra Multiplex (4)
                  • AlphaLISA (49)
                  • AlphaLISA SureFire Ultra (4)
                  • AlphaPlex (2)
                  • LANCE Ultra (26)
                  • Membrane Target Systems (1)
                  • NEN Radiochemicals (38)
                  • Quantum (1)
                  Detection Method
                  • Alpha (63)
                  • Radiometric (39)
                  • Time-Resolved Fluorescence (TRF) (23)
                  • TR-FRET (23)
                  Receptor Type
                  • Ghrelin (1)
                  Assay Validated
                  • Binding (1)
                  Radioisotope
                  • C-14 (23)
                  • H-3 (16)
                  Radionuclide
                  • 14C (1)
                  • 14C (22)
                  • 3H (16)
                  Label Position
                  • 2 positions (1)
                  • Dual labeled at 1 (1)
                  • Generally Labeled (1)
                  • Nominally Labeled (10)
                  • Specifically Labeled (18)
                  • Uniformly Labeled (9)
                  Assay Points (200-50,000)
                  • 100 (37)
                  • 10000 (27)
                  • 500 (63)
                  • 5000 (37)
                  • 50000 (12)
                  Assay Target Class
                  • Cytokine (1)
                  • GPCR (1)
                  • Hormone (32)
                  • Peptide (4)
                  • Phospho-protein (1)
                  • Phosphoprotein (8)
                  • Protein (51)
                  Automation Compatible
                  • Yes (90)
                  Concentration
                  • 0.02 mCi/mL (1)
                  • 0.05 mCi/mL (1)
                  • 0.1 mCi/mL (10)
                  • 0.2 mCi/mL (4)
                  • 1 mCi/mL (12)
                  Experimental Type
                  • In vitro (79)
                  Format
                  • Microplates (60)
                  Host Cell
                  • CHO-K1 (1)
                  Imaging Modality
                  • microCT Imaging (1)
                  Volume
                  • 0-50 (8)
                  • 201-250 (4)

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                  1-25 of 134 Products & Services

                  • Quantum GX2 microCT imaging system

                    Quantum GX2 microCT Imaging System

                    Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
                  • Albumin (human) AlphaLISA Detection Kit

                    AlphaLISA no-wash immunoassay kit for detection of human serum albumin (HSA) in urine, buffered solution, or cell culture medium.
                    Price Range : 3651.00 USD - 28500.00 USD
                  • Albumin (mouse) AlphaLISA Detection Kit

                    The AlphaLISA? Mouse Albumin Detection Kit is designed for the quantitative detection of mouse albumin in serum, urine, buffered solution or cell culture medium, using a homogeneous (no wash steps, no separation steps) assay.
                    Price Range : 3651.00 USD - 28500.00 USD
                  • NNMT (human) AlphaLISA Detection Kit

                    The AlphaLISA? immunoassay kit for human Nicotinamide N-Methyltransferase (NNMT) enables the quantitative determination of human NNMT in buffered solution, cell culture media, and serum using a homogeneous AlphaLISA assay (no wash steps).
                    Price Range : 912.00 USD - 17600.00 USD
                  • Testosterone AlphaLISA Detection Kit

                    The AlphaLISA? Testosterone Research Kit is designed for detection and quantitation of testosterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
                    Price Range : 808.00 USD - 12600.00 USD
                  • Glucagon AlphaLISA Detection kit

                    The AlphaLISA? Glucagon assay is a sandwich immunoassay for quantitative detection of total Glucagon in cellular lysates using Alpha Technology.

                  • LANCE Ultra Biomarker

                    FSH (human) LANCE Ultra TR-FRET Detection Kit

                    The LANCE? Ultra Human Follicle Stimulating Hormone (FSH) Detection Kit is designed for detection and quantitation of human FSH in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
                    Price Range : 877.00 USD - 11700.00 USD
                  • Adenosine 5 Triphosphate 250 μCi

                    Deoxy-D-glucose, 2-[1,2-3H (N)]-, EtOH Sol, Specific Activity: 5-10 Ci (185-370 GBq)/mmol

                    2-Deoxy-D-glucose, nominally labeled with tritium at C1/C2. This product is supplied in 90% ethanol. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.
                    Price Range : 882.00 USD - 1381.00 USD
                  • Alpha SureFire Ultra Multiplex Phospho/Total SMAD2 Assay Kit

                    The AlphaLISA? SureFire? Ultra? Multiplex phospho-SMAD2 (Ser465/467) + Total SMAD2 assay kit is used to measure both the phosphorylation of SMAD2 and total levels of endogenous SMAD2 in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure SMAD2 phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
                    Price Range : 995.00 USD - 63800.00 USD
                  • AlphaLISA SureFire Ultra total-protein

                    Total JNK1/2 AlphaLISA SureFire Ultra Detection Kit

                    The AlphaLISA? SureFire? Ultra? total JNK1/2 assay is a sandwich immunoassay for quantitative detection of JNK1/2 (phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be a normalization phosphorylation studies.

                    Price Range : 553.00 USD - 36700.00 USD
                  • FSH (human) AlphaLISA Detection Kit

                    The AlphaLISA? immunoassay kit for human FSH enables the quantitative determination of human follicle stimulating hormone in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
                    Price Range : 651.00 USD - 19600.00 USD
                  • Diclofenac sodium- Phenylacetic acid C14

                    Glycerol, [14C(U)]

                    Glycerol, uniformly labeled with C-14. 14C-glycerol is commonly used to label carbohydrates.
                    Price Range : 957.00 USD - 3584.00 USD
                  • Adiponectin (human) AlphaLISA Detection Kit

                    The AlphaLISA? Human Adiponectin Detection Kit is designed for detection and quantitation of human adiponectin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
                    Price Range : 1905.00 USD - 12600.00 USD
                  • Cortisol (human) AlphaLISA Detection Kit

                    AlphaLISA no-wash immunoassay kit for detection of human cortisol in buffer or serum.
                    Price Range : 872.00 USD - 12600.00 USD
                  • Sucrose, [14C(U)]-, Specific Activity: 400-700mCi (14.8-25.9GBq)/mmol

                    Sucrose, labeled with C-14. 14C-sucrose is commonly used to study blood-brain barrier permeability.
                    Price Range : 642.00 USD - 3802.00 USD
                  • LANCE Ultra Biomarker

                    Apo-CIII (human) LANCE Ultra TR-FRET Detection Kit

                    The LANCE? Ultra Human Apo-CIII Detection Kit is designed for detection and quantitation of ApoC3 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
                    Price Range : 877.00 USD - 11700.00 USD
                  • IGF-1 (rat) AlphaLISA Detection Kit

                    The AlphaLISA? immunoassay kit for rat IGF-1 enables the quantitative determination of rat insulin-like growth factor 1 (IGF-1) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
                    Price Range : 752.00 USD - 22500.00 USD
                  • hCG (human) AlphaLISA Detection Kit

                    The AlphaLISA? immunoassay kit for human chorionic gonadotropin (hCG) enables the quantitative determination of hCG in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
                    Price Range : 651.00 USD - 19600.00 USD
                  • Leptin (mouse) AlphaLISA Detection Kit

                    The AlphaLISA? Mouse Leptin Detection Kit is designed for detection and quantitation of mouse leptin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
                    Price Range : 1851.00 USD - 12300.00 USD
                  • Albumin (human) AlphaLISA Biotin-Free Detection Kit

                    The AlphaLISA? Human Albumin Biotin-Free Detection Kit is designed for the quantitative detection of human albumin in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
                    Price Range : 559.00 USD - 12200.00 USD
                  • PerkinElmer

                    IGF-1 (rat), lyophilized (LANCE)

                    Rat IGF-1 (insulin-like growth factor 1) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra rat IGF-1 Detection Kit, but can also be ordered separately.
                    List Price : 335.00 USD
                  • KIM-1 (human) AlphaLISA Detection Kit

                    The AlphaLISA? immunoassay kit for human Kidney Injury Molecule 1 (KIM-1) enables the quantitative determination of human KIM-1 in buffered solution, urine, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
                    Price Range : 912.00 USD - 17600.00 USD
                  • PON-2 (human) AlphaLISA Detection Kit

                    The AlphaLISA? immunoassay kit for human PON-2 enables the quantitative determination of human Paraoxonase 2 (PON-2) in buffered solution, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
                    Price Range : 912.00 USD - 17600.00 USD
                  • AlphaLisa Analyte 2

                    ApoB (human), lyophilized (AlphaLISA)

                    Human ApoB standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human ApoB Detection Kit, but can also be ordered separately.
                    List Price : 370.00 USD
                  • AlphaLISA Sandwich Anti-AnalyteConjugatedAcceptorBead

                    TSH (human) AlphaLISA Detection Kit

                    The AlphaLISA? immunoassay kit for human TSH enables the quantitative determination of human thyroid stimulating hormone (TSH) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
                    Price Range : 774.00 USD - 23300.00 USD
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                  澳门新用户注册送88